Atrial Fibrillation

Cardiology

Supraventricular tachyarrhythmia with uncoordinated atrial activation and irregular ventricular response.

Causes

  • • HTN, HF, valvular disease
  • • Thyroid disease, alcohol
  • • Sepsis, PE, post-op
  • • Lone AF

Clinical features

  • • Palpitations, dyspnoea, chest pain, dizziness
  • • Asymptomatic in 30%

Investigations

  • • 12-lead ECG
  • • TSH, U&E, TFT, LFT
  • • Echo (structural)
  • • Ambulatory monitoring if paroxysmal

Management

  • • Rate control: β-blocker/CCB (target HR <110 lenient, <80 strict)
  • • Rhythm control if symptomatic: DC cardioversion / flecainide (structurally normal) / amiodarone / ablation
  • • Anticoagulation per CHA2DS2-VASc (≥2 M / ≥3 F)

Drug therapy

  • • DOAC first-line (apixaban preferred in elderly/CKD)
  • • LAA closure if OAC contraindicated
  • • AAD: flecainide, sotalol, amiodarone

Complications

  • • Stroke (5× ↑ risk)
  • • HF, tachy-cardiomyopathy
  • • Cognitive decline

Clinical pearls

  • • ABC pathway: Anticoag, Better symptom control, Cardiovascular risk mgmt
  • • Early rhythm control in HF (EAST-AFNET 4)

References

  • • ESC 2020 AF Guidelines
  • • AHA/ACC 2023 AF

Related in WardRound

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