Emergency Drugs · α/β adrenergic agonist
Adrenaline (Epinephrine)
Brand: Adrenaline 1:1000 / 1:10,000
Dose
Anaphylaxis: 0.5 mg IM (1:1000). Arrest: 1 mg IV (1:10,000) q3–5 min. Infusion: 0.05–0.5 mcg/kg/min.
Mechanism
Indications
- • Anaphylaxis
- • Cardiac arrest
- • Severe bronchospasm
- • Refractory shock
Contraindications
- • No absolute in emergencies
Dose adjustment
Dilution & preparation
1 mg in 100 mL D5W or NS for infusion (10 mcg/mL)
Administration
Use
Monitoring
Side effects
- • Tachyarrhythmias
- • Hypertension
- • Anxiety / tremor
- • Myocardial ischaemia
- • Extravasation necrosis
Pregnancy safety
Related in WardRound
Adrenaline (Epinephrine) dilution
Dilution · 1 mg / 50 mL D5W → 20 mcg/mL
Adrenaline dose calculator
Dose · Refractory shock, anaphylaxis infusion
Shock
Protocol · Hypoperfusion / circulatory failure
Sepsis
Protocol · Sepsis Six within 1 hour
Cardiogenic Shock
Protocol · Pump failure
Anaphylaxis
Protocol · Adrenaline first, every time
Upper GI Bleed
Protocol · Blatchford / Rockall
Cardiac Arrest
Protocol · ALS algorithm
Sepsis & Septic Shock (ED)
Topic · Emergency Medicine
Anaphylaxis
Topic · Emergency Medicine
Bradycardia Approach
Topic · Cardiology
Cardiac Arrest Overview
Topic · Emergency Medicine
β-Blocker Overdose
Topic · Toxicology
Calcium Channel Blocker Overdose
Topic · Toxicology
Always confirm dose against your local formulary / BNF before prescribing.
