First 30 seconds
- 1Recognise red-flag sepsis
- 2Call senior + activate sepsis pathway
- 3O₂ to target SpO₂ 94–98%
- 4IV access, bloods + lactate
- 5Start fluid bolus
Life-threatening organ dysfunction due to dysregulated host response to infection (SOFA ≥ 2).
A
Airway
- • Patent? Talking? Stridor?
- • Suction, jaw-thrust, adjuncts, definitive airway if needed
B
Breathing
- • RR, SpO₂, auscultate, percuss
- • O₂ to target sats, NIV / intubate as required
C
Circulation
- • HR, BP, cap refill, JVP
- • 2× large-bore IV, bloods, monitor, ECG
D
Disability
- • AVPU/GCS, pupils, glucose, temp
E
Exposure
- • Full exposure, skin, rash, bleeding, lines, infection source
