Excess adiposity (BMI ≥30 kg/m², or ≥27.5 in South Asian populations) with adverse metabolic and mechanical consequences.
Investigations
- • BMI, waist circumference, BP
- • HbA1c, lipids, LFTs (NAFLD), TFT
- • Screen OSA (STOP-BANG), depression
Management
- • Structured lifestyle: 500–750 kcal/day deficit + 150 min/week activity
- • Pharmacotherapy: GLP-1 RA (semaglutide 2.4 mg, liraglutide 3 mg), orlistat
- • Bariatric surgery if BMI ≥40, or ≥35 with comorbidity
- • Post-bariatric lifelong micronutrient supplementation
Clinical pearls
- • Weight regain after stopping GLP-1 therapy is expected — plan long-term strategy
- • Screen for and treat OSA before elective surgery
Related in WardRound
Educational — verify locally.
