First 30 seconds
- 1Remove trigger
- 2Adrenaline 0.5 mg (0.5 mL 1:1000) IM anterolateral thigh
- 3Call for help, lay flat + legs up
- 4O₂ 15 L/min
- 5IV access, fluid bolus 500–1000 mL
Severe, life-threatening, generalised hypersensitivity — airway, breathing, circulation involvement + usually skin signs.
A
Airway
- • Patent? Talking? Stridor?
- • Suction, jaw-thrust, adjuncts, definitive airway if needed
B
Breathing
- • RR, SpO₂, auscultate, percuss
- • O₂ to target sats, NIV / intubate as required
C
Circulation
- • HR, BP, cap refill, JVP
- • 2× large-bore IV, bloods, monitor, ECG
D
Disability
- • AVPU/GCS, pupils, glucose, temp
E
Exposure
- • Full exposure, skin, rash, bleeding, lines, infection source
