Emergency Drugs · Antimuscarinic
Atropine
Dose
500 mcg IV bolus, repeat to 3 mg (bradycardia). OP poisoning: 2–5 mg q5 min, double until atropinised.
Mechanism
Competitive muscarinic antagonist
Indications
- • Symptomatic bradycardia
- • Organophosphate poisoning
- • Pre-medication for intubation
Use
Bradycardia with adverse features, OP poisoning.
Monitoring
HR, BP, secretions, pupils.
Side effects
- • Dry mouth
- • Mydriasis
- • Urinary retention
- • Tachyarrhythmia
Related in WardRound
Organophosphorus Poisoning
Protocol · Cholinergic crisis — SLUDGE/DUMBELS
Snake Bite
Protocol · ASV indication
Bradycardia
Protocol · Adverse features?
Complete Heart Block
Protocol · Atropine → pacing
Digoxin Toxicity
Protocol · DigiFab + correct K
β-blocker Overdose
Protocol · Glucagon + high-dose insulin
Bradycardia Approach
Topic · Cardiology
β-Blocker Overdose
Topic · Toxicology
Calcium Channel Blocker Overdose
Topic · Toxicology
Digoxin Toxicity
Topic · Toxicology
Always confirm dose against your local formulary / BNF before prescribing.
