Tranexamic Acid

Haematology

Haematology · Antifibrinolytic

Tranexamic Acid

Dose

1 g IV over 10 min then 1 g over 8 h (trauma/PPH); 1 g PO TDS for menorrhagia.

Contraindications

  • Active intravascular clotting
  • Subarachnoid haemorrhage (relative)

Use

Trauma haemorrhage within 3 h, PPH, menorrhagia, epistaxis, surgical bleeding.

Monitoring

Clinical bleeding; caution with prior thrombosis.

Side effects

  • Nausea, diarrhoea
  • Visual disturbance with prolonged use
  • Seizures at high IV dose

Related in WardRound

Always confirm dose against your local formulary / BNF before prescribing.

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