Propranolol (variceal prophylaxis)

Gastroenterology

Gastroenterology · Non-selective β-blocker

Propranolol (variceal prophylaxis)

Dose

20–40 mg PO BD; titrate to HR 55–60/min or maximum tolerated dose.

Use

Primary and secondary prophylaxis of variceal bleeding in cirrhosis.

Monitoring

HR, BP, tolerance; withhold in refractory ascites with SBP <90 or hyponatraemia <130.

Side effects

  • Fatigue
  • Bradycardia
  • Hypotension
  • Bronchospasm

Related in WardRound

Always confirm dose against your local formulary / BNF before prescribing.

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