Acute Ischaemic Stroke

Neurology

Focal neurological deficit from cerebral vessel occlusion.

Investigations

  • Non-contrast CT (exclude bleed)
  • CT angiography (LVO for thrombectomy)
  • Glucose, coag, ECG, troponin

Management

  • Thrombolysis with alteplase 0.9 mg/kg (max 90) if <4.5 h and no contraindications
  • Tenecteplase 0.25 mg/kg (max 25) alternative
  • Mechanical thrombectomy for LVO up to 24 h (imaging-selected)
  • Aspirin 300 mg from 24 h post-lytic
  • BP <185/110 pre-lytic; <220/120 otherwise

Complications

  • Haemorrhagic transformation, cerebral oedema

Related in WardRound

Educational — verify locally.

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