Pleural Effusion

Respiratory

Pathological accumulation of fluid in the pleural space, classified as transudate or exudate by Light's criteria.

Investigations

  • CXR (blunted costophrenic angle) and thoracic ultrasound before any tap
  • Pleural fluid protein, LDH, pH, glucose, cytology, culture
  • Serum protein and LDH for Light's criteria
  • CT with contrast if exudative and undiagnosed

Management

  • Treat the cause: diuretics for heart failure transudate
  • Chest drain if empyema, pH <7.2 or frank pus
  • Therapeutic aspiration ≤1.5 L at a time (re-expansion oedema)
  • Indwelling pleural catheter or talc pleurodesis for malignant effusion

Clinical pearls

  • Light's criteria over-call exudates in diuresed heart failure — use serum-effusion albumin gradient >12 g/L
  • Never insert a drain without ultrasound guidance

Related in WardRound

Educational — verify locally.

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