Metastatic Spinal Cord Compression

Oncology

Compression of the cord or cauda equina by tumour, causing irreversible neurological deficit if untreated.

Clinical features

  • • Progressive back pain worse on lying flat or coughing
  • • Band-like radicular pain
  • • Leg weakness, sensory level
  • • Bladder/bowel dysfunction (late)

Investigations

  • • Whole-spine MRI within 24 h (immediately if neurological signs)
  • • Search for a primary if unknown

Management

  • • Dexamethasone 16 mg PO with PPI immediately
  • • Flat bed rest with log-rolling until stability assessed
  • • Discuss with oncology/spinal surgery within 24 h
  • • Radiotherapy or surgical decompression
  • • Analgesia and VTE prophylaxis

Clinical pearls

  • • Ambulatory status at treatment is the strongest predictor of walking afterwards — treat before weakness develops

Educational — verify locally.

WardRound

WardRound

Clinical Decisions in Seconds