Prolonged ventricular repolarisation → torsades and SCD risk.
Causes
- • Congenital (LQT1-15; LQT1 most common)
- • Acquired: drugs (quinolones, macrolides, antipsychotics, antifungals), electrolytes (↓K, Mg, Ca), hypothyroidism
Diagnosis
- • QTc >460 ms F / >450 ms M (Bazett); >500 high risk
- • Schwartz score for congenital
Management
- • Avoid triggers (LQT1: exercise/swim; LQT2: startle/postpartum; LQT3: rest)
- • β-blocker (nadolol preferred)
- • ICD if aborted SCD/syncope on β-blocker
- • Correct electrolytes; withdraw offending drugs
Related in WardRound
Educational — verify locally.
