Anorexia Nervosa & Refeeding Risk

Psychiatry

Restriction of intake leading to significantly low weight, intense fear of weight gain and disturbed body image.

Investigations

  • Weight, BMI, sit-up–squat–stand test
  • U&E, phosphate, magnesium, glucose, FBC, LFT
  • ECG for bradycardia and prolonged QTc
  • DEXA if amenorrhoeic >1 year

Management

  • Specialist eating-disorder service referral
  • Psychological therapy (CBT-ED, MANTRA, family therapy for young people)
  • Cautious refeeding 5–10 kcal/kg/day if high risk
  • Thiamine and multivitamins before feeding
  • Daily phosphate, potassium and magnesium for first week

Complications

  • Refeeding syndrome — hypophosphataemia, arrhythmia, cardiac failure
  • Osteoporosis
  • Infertility

Clinical pearls

  • Highest mortality of any psychiatric disorder
  • Rapid weight loss matters more than absolute BMI for admission decisions

Related in WardRound

Educational — verify locally.

WardRound

WardRound

Clinical Decisions in Seconds