Cardiogenic Shock

Cardiology

End-organ hypoperfusion from primary cardiac dysfunction: SBP <90 for >30 min or vasopressors to maintain, with hypoperfusion signs.

Causes

  • Large MI (>40% LV loss)
  • Mechanical complications (VSR, MR, tamponade)
  • Fulminant myocarditis
  • Decompensated HF
  • Massive PE, arrhythmia

Clinical features

  • Cool clammy skin, oliguria, altered mental state
  • Hypotension

Investigations

  • Bedside echo, ECG, troponin, lactate, ABG
  • PA catheter (CI <2.2, PCWP >15)
  • Coronary angiography if ACS

Management

  • Immediate revascularisation (culprit-only PCI, CULPRIT-SHOCK)
  • Vasopressor (norad) + inotrope (dobutamine or milrinone)
  • IABP not routinely (IABP-SHOCK II)
  • Consider Impella, VA-ECMO
  • Correct mechanical complications surgically

Complications

  • Multiorgan failure
  • Bowel ischaemia
  • Bleeding on MCS

Clinical pearls

  • Mortality 40-50%
  • Early transfer to CS centre with MCS

References

  • ESC 2021 HF Guidelines
  • SCAI Shock Classification 2019

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