DOAC Reversal

Agent-specific

Dabigatran

  • Idarucizumab 5 g IV (2 × 2.5 g)
  • Haemodialysis (highly dialysable)

Apixaban / Rivaroxaban

  • Andexanet alfa (where available)
  • PCC 50 U/kg if andexanet not available

Edoxaban

  • PCC 50 U/kg

General

  • Tranexamic acid 1 g IV
  • Activated charcoal if ingestion <2 h
WardRound

WardRound

Clinical Decisions in Seconds