Viral Upper Respiratory Infection

General Medicine

Self-limiting viral URTI (common cold) — rhinorrhoea, sore throat, mild cough, low-grade fever lasting 7–10 days.

History taking

  • Nasal discharge, sneezing, sore throat, cough
  • Low-grade fever, malaise, headache
  • Contact with cases
  • Vaccination, comorbidities

Examination

  • Vitals (usually normal or low-grade fever)
  • Throat: erythema without exudate
  • No tonsillar swelling / cervical LN
  • Clear chest

Red flags

  • RR >24, SpO₂ <94%
  • Stridor, drooling, severe sore throat (epiglottitis)
  • Symptoms >10 days or biphasic course (bacterial superinfection)

Differential diagnosis

  • Streptococcal pharyngitis (Centor)
  • Influenza, COVID-19
  • Allergic rhinitis
  • Acute bacterial sinusitis

Recommended investigations

  • Clinical diagnosis
  • RAT for COVID/influenza if at risk or during outbreak
  • FBC/CRP only if uncertain or severe

Diagnosis

  • Clinical based on symptoms <10 d and absent red flags

Initial treatment / management

  • Symptomatic care: rest, hydration, paracetamol
  • Saline nasal douche, steam
  • No routine antibiotics

Drug therapy

  • Paracetamol 1 g PO QDS PRN (max 4 g/d)
  • Xylometazoline 0.1% nasal spray BD × 5 d for congestion
  • Honey for cough in adults / >1 y

Lifestyle advice

  • Hand hygiene
  • Cover cough
  • Stay home until afebrile 24 h

Prescription examples

  • Paracetamol 500 mg — 1–2 tab QDS × 5 d
  • Saline nasal drops PRN

Follow-up advice

  • Return if fever >7 d, breathlessness, or symptoms worsening after improvement

Patient counselling

  • Antibiotics do not help viral illness
  • Expected duration 7–10 d; cough may persist 3 weeks

Referral criteria

  • Refer if persistent fever, complicated sinusitis, or recurrent (>6/year in adults)

Clinical pearls

  • Antibiotics for URTI are over-prescribed — use Centor / FeverPAIN for pharyngitis

References

  • NICE NG79 Cough acute 2019
  • WHO IMCI

Educational outpatient guide — verify against local guidelines before clinical use.

WardRound

WardRound

Clinical Decisions in Seconds