Recurrent UTI

Nephrology

≥2 UTIs in 6 months or ≥3 in 12 months.

History taking

  • • Onset, duration, progression, severity
  • • Aggravating / relieving factors
  • • Past history, drugs, allergies, comorbidities
  • • Family & social history relevant to presentation

Examination

  • • General: vitals, pallor, icterus, oedema, lymphadenopathy
  • • Focused system examination
  • • Look for red-flag findings

Red flags

  • • Haemodynamic instability
  • • Rapid deterioration
  • • Severe pain or new neurological deficit

Differential diagnosis

  • • See differentials section per chief complaint

Recommended investigations

  • • Urine MCS during episode
  • • USS KUB, post-void residual
  • • Cystoscopy if persistent / atypical

Diagnosis

  • • Clinical diagnosis supported by targeted investigations

Initial treatment / management

  • • Treat underlying cause
  • • Symptomatic relief
  • • Patient education

Drug therapy

  • • Acute: per local guidelines
  • • Prophylaxis: nitrofurantoin 50 mg ON or trimethoprim 100 mg ON for 6 months
  • • Post-coital prophylaxis option

Follow-up advice

  • • Review in 2–4 weeks or earlier if worsening
  • • Monitor response to therapy and adverse effects

Patient counselling

  • • Hydration, post-coital voiding, wipe front-to-back
  • • Topical vaginal oestrogen post-menopause

Referral criteria

  • • Refer if diagnostic uncertainty, complications, or failure of first-line therapy

References

  • • Harrison's Principles of Internal Medicine, 21e
  • • NICE / WHO guidelines (current edition)

Educational outpatient guide — verify against local guidelines before clinical use.

WardRound

WardRound

Clinical Decisions in Seconds