Sepsis Hour-1 Bundle: A Quick Refresher

Lactate, cultures, broad-spectrum antibiotics, 30 mL/kg crystalloid for hypotension or lactate ≥4, and vasopressors to keep MAP ≥65.

WHO Highlights Rising Antimicrobial Resistance

Global surveillance shows continued rise in carbapenem-resistant Enterobacterales; stewardship and infection control remain priorities.

ICMR Advisory: Dengue Preparedness for Monsoon

Early recognition of warning signs and judicious fluid therapy reduce dengue mortality.

CDC: Resurgent Measles in Under-Vaccinated Communities

Measles is highly contagious; isolate suspected cases and verify MMR status of contacts within 72 h.

NIH-Funded Trial: Extended Window Thrombectomy

Selected large-vessel occlusion patients benefit from mechanical thrombectomy up to 24 h with favourable imaging.

Acute Coronary Syndrome: Initial 10 Minutes

ECG within 10 min, dual antiplatelet, anticoagulation, and rapid reperfusion decision define early ACS care.

PubMed Roundup: GLP-1 Agonists Beyond Diabetes

Emerging evidence supports cardiovascular and renal benefits of GLP-1 receptor agonists in selected non-diabetic populations.

MoHFW: National TB Elimination Programme Update

Shorter all-oral regimens for drug-resistant TB are being scaled up under NTEP.

Drug Safety: Fluoroquinolone Restrictions Reinforced

Avoid fluoroquinolones for uncomplicated UTI, sinusitis, or bronchitis when alternatives exist.

Anaphylaxis: IM Adrenaline First, Always

Intramuscular adrenaline 0.01 mg/kg (max 0.5 mg) anterolateral thigh is first-line; repeat every 5–15 min as needed.

Paediatric Maintenance Fluids: Isotonic Is Standard

Use isotonic crystalloid (e.g., 0.9% saline or balanced solutions) with dextrose for paediatric maintenance to prevent hyponatraemia.

Severe Pre-eclampsia: Magnesium and BP Control

MgSO4 4–6 g IV load then 1–2 g/h infusion for seizure prophylaxis; labetalol/hydralazine/nifedipine for BP ≥160/110.

AKI: KDIGO Staging at the Bedside

Stage by creatinine rise or urine output; address pre-renal, renal, and post-renal causes simultaneously.

Perioperative VTE Prophylaxis: Risk-Based Approach

Use Caprini or Rogers scores to guide mechanical vs pharmacological prophylaxis.

Febrile Neutropenia: Antibiotics Within 60 Minutes

ANC <500 (or <1000 with predicted fall) plus fever ≥38.3 °C once or ≥38 °C for 1 h: empirical broad-spectrum within 1 h.

NCDC: Leptospirosis Alert in Monsoon Zones

Consider lepto in fever with myalgia, conjunctival suffusion, jaundice, or AKI after monsoon exposure.

Medical Education: Structuring an OSCE Station Answer

Greet, consent, structured history/exam, summarise, and offer a differential with a clear plan.