Proteinuria + haematuria + RBC casts
Common causes
- • Glomerulonephritis
- • Vasculitis
- • Lupus nephritis
Significance: Active urinary sediment — nephrology referral.
Differential diagnosis
- • Post-strep GN
- • IgA nephropathy
- • ANCA vasculitis
- • Lupus nephritis
Next investigations
- • 24h urine protein / UPCR
- • ANA, ANCA, anti-dsDNA, C3/C4
- • Renal biopsy
Red flags
- • Rapidly progressive renal failure
- • Pulmonary haemorrhage (Goodpasture)
