Cardiac Biomarkers

Cardiology

High-sensitivity troponin, CK-MB, BNP/NT-proBNP.
hsTnCK-MBBNPNT-proBNP

Raised troponin

Common causes

  • • ACS
  • • Myocarditis
  • • PE
  • • Sepsis
  • • CKD
  • • Tachyarrhythmia

Significance: Use 0/1h or 0/3h pathway and clinical context (chest pain + ECG).

Differential diagnosis

  • • STEMI/NSTEMI
  • • Type 2 MI
  • • Myocarditis
  • • Takotsubo

Next investigations

  • • Serial troponin
  • • 12-lead ECG
  • • Echo
  • • Coronary angiography if indicated

Red flags

  • • Dynamic rise/fall with chest pain
  • • ST elevation = activate cath lab

Educational support only — not a substitute for clinical judgment.

WardRound

WardRound

Clinical Decisions in Seconds