SSC 2021 / 2024 hour-1 bundle.
Within 1 hour
- • Measure lactate
- • Blood cultures before antibiotics
- • Broad-spectrum antibiotics
- • 30 mL/kg crystalloid if hypotension/lactate ≥4
- • Vasopressors to MAP ≥65 if persistent hypotension
Within 6 hours
- • Reassess volume status
- • Re-measure lactate
- • Source control
Pearls
- • Door to antibiotic <60 min
- • qSOFA / NEWS for early recognition
Educational support only — follow institutional ICU protocols.
