Myxoedema Coma

Severe hypothyroidism with decompensation

First 30 seconds

  1. 1ABCDE + passive rewarming (avoid rapid)
  2. 2IV access, bloods (TFT, cortisol, glucose, Na, FBC, septic screen)
  3. 3Glucose if low
  4. 4Hydrocortisone BEFORE thyroxine

End-stage hypothyroidism with hypothermia, altered mental state, multi-organ decompensation; mortality up to 40%.

A

Airway

  • Patent? Talking? Stridor?
  • Suction, jaw-thrust, adjuncts, definitive airway if needed
B

Breathing

  • RR, SpO₂, auscultate, percuss
  • O₂ to target sats, NIV / intubate as required
C

Circulation

  • HR, BP, cap refill, JVP
  • 2× large-bore IV, bloods, monitor, ECG
D

Disability

  • AVPU/GCS, pupils, glucose, temp
E

Exposure

  • Full exposure, skin, rash, bleeding, lines, infection source
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WardRound

WardRound

Clinical Decisions in Seconds