Sucralfate

Gastroenterology

Gastroenterology · Mucosal protectant

Sucralfate

Dose

1 g PO QDS on empty stomach (1 h before meals and at bedtime).

Use

Mucosal protection in ulcers, bile reflux gastritis, radiation proctitis.

Monitoring

Separate other drugs by ≥2 h (chelation), aluminium accumulation in CKD.

Side effects

  • Constipation
  • Reduced absorption of quinolones, levothyroxine, phenytoin

Always confirm dose against your local formulary / BNF before prescribing.

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