Neurology · Glutamate release inhibitor
Riluzole
Dose
50 mg PO BD, 1 h before or 2 h after food.
Use
Motor neurone disease — prolongs survival ~3 months.
Monitoring
LFTs monthly × 3 then 3-monthly, FBC if febrile.
Side effects
- • Nausea
- • Fatigue
- • Transaminitis
- • Neutropenia (rare)
Always confirm dose against your local formulary / BNF before prescribing.
