Respiratory · Anti-fibrotic
Pirfenidone
Dose
267 mg TDS week 1 → 534 mg TDS week 2 → 801 mg TDS maintenance, with food.
Use
Idiopathic pulmonary fibrosis — slows FVC decline.
Monitoring
LFTs monthly × 6 then 3-monthly, weight, photosensitivity precautions.
Side effects
- • Photosensitive rash
- • Nausea, anorexia
- • Transaminitis
- • Fatigue
Related in WardRound
Always confirm dose against your local formulary / BNF before prescribing.
