Misoprostol

Emergency Drugs

Emergency Drugs · Prostaglandin E1 analogue

Misoprostol

Dose

PPH: 800 mcg sublingual or PR. Medical management of miscarriage: per local protocol.

Use

Second-line uterotonic where oxytocin unavailable or refractory atony.

Monitoring

Temperature (pyrexia common), bleeding, uterine tone.

Side effects

  • Fever, shivering
  • Diarrhoea
  • Nausea

Related in WardRound

Always confirm dose against your local formulary / BNF before prescribing.

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Clinical Decisions in Seconds