Memantine

Neurology

Neurology · NMDA receptor antagonist

Memantine

Dose

5 mg OD, increase 5 mg weekly to 20 mg OD. Max 10 mg/day if eGFR 5–29.

Use

Moderate-to-severe Alzheimer's disease; may be combined with donepezil.

Monitoring

Renal function, confusion, behavioural response.

Side effects

  • Dizziness
  • Headache
  • Constipation
  • Hallucinations

Related in WardRound

Always confirm dose against your local formulary / BNF before prescribing.

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