Analgesia · Synthetic opioid (µ agonist)
Fentanyl
Dose
IV 25–100 mcg q1–2h PRN; infusion 25–200 mcg/h; lozenge / patch chronic
Mechanism
Potent µ-receptor agonist (~100× morphine)
Indications
- • Acute severe pain
- • Anaesthesia adjunct
- • Procedural analgesia
Use
Rapid onset (~1 min), short duration; haemodynamically stable.
Monitoring
RR, sedation, SpO₂, pain score.
Side effects
- • Respiratory depression
- • Chest-wall rigidity (large bolus)
- • Bradycardia
- • Pruritus
Pregnancy safety
Use if needed; neonatal respiratory depression if near delivery
Always confirm dose against your local formulary / BNF before prescribing.
