Syncope Assessment

Cardiac vs reflex vs orthostatic

Red flags
  • Syncope during exertion
  • Family history SCD
  • Abnormal ECG (long QT, Brugada, HCM, WPW)
  • Structural heart disease
  • Sudden collapse without prodrome

First steps

  • Full history: prodrome, triggers, witnesses, injury
  • 12-lead ECG + orthostatic BP
  • Cardiac exam

Key investigations

  • 12-lead ECG
  • Echo if structural heart disease suspected
  • Tilt table if vasovagal likely
  • Holter/loop recorder if arrhythmia suspected

Differentials

  • Vasovagal
  • Orthostatic hypotension
  • Cardiac (arrhythmia, structural)
  • Seizure
  • Hypoglycaemia

Initial management

  • Vasovagal: education, hydration, counter-manoeuvres
  • Orthostatic: review drugs, compression stockings, midodrine
  • Cardiac: treat cause; ICD if life-threatening VT

Referral

  • Cardiology for cardiac cause
  • Neurology if seizure/TIA suspected
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