Sepsis Assistant

Hour-1 bundle

Red flags
  • qSOFA ≥2
  • Lactate >2 mmol/L
  • Persistent hypotension despite fluids

First steps

  • Recognize, escalate, draw labs + 2 sets cultures
  • Lactate, blood gas, CBC, CRP, procalcitonin

Key investigations

  • Source identification: CXR, urine, USG, CT
  • Repeat lactate at 2–4 h

Differentials

  • Pneumonia, UTI, intra-abdominal, skin/soft tissue, CNS, catheter-related

Initial management

  • Broad-spectrum antibiotics within 1 h
  • 30 ml/kg crystalloid for hypotension/lactate >4
  • Vasopressor to MAP ≥65 (noradrenaline)
  • Source control

Referral

  • ICU
  • Surgical source control

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